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Acura MDX vs. Lexus TX 350

Shop Acura MDX Inventory

If you're shopping for a premium three-row SUV, the 2026 Acura MDX and 2026 Lexus TX 350 offer two distinct approaches to luxury, performance and everyday versatility. Both provide seating for up to seven passengers, advanced driver-assist technology and upscale interiors, but there are important differences worth considering.

2026 Acura MDX vs. 2026 Lexus TX 350

2026 Acura MDX versus 2026 Lexus TX 350 comparison chart

MDX Performance Comes Standard With V6 Power

The 2026 Acura MDX is powered by a 3.5-liter V6 producing 290 horsepower and paired with a 10-speed automatic transmission. Front-wheel drive is available on select models, while Acura's Super Handling All-Wheel Drive™ (SH-AWD®) is available throughout much of the lineup.

Drivers looking for even more performance can step up to the MDX Type S Advance, which uses a turbocharged 3.0-liter V6 producing 355 horsepower.

The 2026 Lexus TX 350 takes a different approach with a 2.4-liter turbocharged four-cylinder producing 275 horsepower. Front-wheel drive and all-wheel drive configurations are available.

For drivers who prefer the smooth power delivery and character of a naturally aspirated V6, the MDX offers something the turbocharged four-cylinder TX 350 does not.

2026 Acura MDX

Three Rows of Flexible Seating

Both SUVs can accommodate up to seven passengers.

The MDX features a versatile second row with a removable center seat. Leave it installed for seven-passenger seating or remove it to create a captain's-chair-style configuration and easier access to the third row.

The Lexus TX 350 is also available with seating for seven, while selected configurations provide six-passenger seating with second-row captain's chairs.

Both vehicles offer the flexibility families expect from a premium three-row SUV.

Technology for Every Drive

The 2026 MDX combines its performance-oriented design with modern cabin technology, including Google built-in and a panoramic moonroof standard across the lineup. Available features include a head-up display, premium audio, heated second-row seating and other upscale amenities depending on package.

The Lexus TX also offers a modern technology-focused cabin, including a 14-inch Lexus Interface touchscreen and Lexus Safety System+ 3.0 as standard equipment.

Acura MDX vs. Lexus TX 350: Which Is Right for You?

The Lexus TX 350 offers an especially spacious three-row cabin and generous cargo capacity, making it a strong choice for shoppers who put maximum interior space near the top of their list.

The Acura MDX offers a different balance. Its standard V6 produces more horsepower than the TX 350's turbocharged four-cylinder, while its available SH-AWD® system, double-wishbone front suspension and performance-focused Type S model give drivers several ways to add capability and excitement.

The 2026 MDX also carries a lower manufacturer-listed starting price than the 2026 TX 350.

For luxury SUV shoppers who want three-row versatility without giving up engaging performance, the 2026 Acura MDX deserves a close look.

Experience the 2026 Acura MDX at Flow Acura

See how the MDX compares for yourself. Explore our available Acura MDX inventory or visit Flow Acura in Winston-Salem to experience its performance, interior versatility and technology firsthand.

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